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dr. uzelac's publications

Live birth following in vitro maturation of oocytes retrieved from extracorporeal ovarian tissue aspiration and embryo cryopreservation for 5 years.

Objective To report a live birth after in vitro maturation (IVM) of oocytes retrieved from extracorporeal ovarian tissue aspiration in the setting of fertility preservation. Design Observational study. Setting Academic center. Patient(s) A 23-year-old woman. Intervention(s) IVM from extracorporeal ovarian tissue aspiration. Main Outcome Measure(s) Live birth after IVM. Result(s) A 23-year-old woman conceived with embryos read more >>

The Role of In Vitro Maturation in Fertility Preservation

In vitro maturation (IVM) is an advanced embryology laboratory technique whereby immature oocytes, which are removed from ovarian follicles prior to completing their growth in vivo, are cultured from the germinal vesicle (GV) to the metaphase II (MII) stage. Upon reaching maturity in vitro, these eggs can then be fertilized and the resulting embryos can read more >>

In vitro maturation of human immature oocytes for fertility preservation.

Cryopreservation of embryos, oocytes, or ovarian tissues is the main option for female fertility preservation. Oocyte cryopreservation has emerged as especially important: the dramatic increase in the number of infants born from vitrified oocytes indicates that it is becoming one of the most important intervention options. However, oocyte cryopreservation with standard controlled ovarian hyperstimulation may read more >>

Moderate IVF treatment for advanced reproductive age women

Objective: A growing body of literature suggests that, among some infertility patient populations, mild approaches in assisted reproductive technology (ART) may result in similar outcomes when compared to those utilizing controlled ovarian hyperstimulation (COH). Given the well-recognized decline in success of conventional in vitro fertilization (IVF) with age, it is unclear whether mild approaches in read more >>

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